Does MOTS-c improve metabolism?
Check for CB4211, a related experimental compound. Its trial registration describes testing safety and how the drug behaves in the body. That record isn’t a result for MOTS-c itself.
7 of 16 in Every Peptide Explained in 10 Minutes (Human Studies Only)
What the human studies found
- A peptide your own mitochondria make, promoted for metabolism.
- The CB4211 record describes a randomized, placebo-controlled study of safety, tolerability and how the drug behaves in the body, in healthy non-obese adults and people with fatty liver disease.
- That record isn’t a result for MOTS-c itself.
- A new registry record from a sponsor in Shenzhen had no results posted as of October 2, 2026.
The studies (2)


Also cited
- ClinicalTrials.gov NCT07505745 (MOTS-c, sponsor-submitted, no results posted as of October 2, 2026)
- 2026 review describing how it’s promoted · PubMed 41966639
We checked the human research behind 16 peptides. The question wasn’t just “is there a study?” It was “does that study support the pitch?” For each one: who took part, what was measured, and what actually changed.
Watch all 16, explained: the film on YouTube · 9:42An approval, a trial or a paper belongs to a particular substance and a particular use. None of it verifies the contents of a bottle sold online. This is an investigation of the claims, not a guide to taking them.
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The three questions we asked of all 16 peptides, plus each new investigation when it drops. No spam, unsubscribe anytime.